Top-Rated Supplements for Digestion, Gut Health & Immunity
Digestive issues are one of the most common problems dogs face—ranging from diarrhea and constipation to gas, allergies, and poor nutrient absorption. A high-quality probiotic for dogs can help restore gut balance, support immune health, and keep your pup feeling their best.
In this guide, we’ve rounded up 10 of the best dog probiotics available on Amazon, including soft chews and capsules. These picks are popular with pet parents, highly rated, and formulated to support digestion, stool quality, and overall wellness.
🛑 Important: Always consult your veterinarian before starting a new supplement, especially if your dog has chronic digestive issues, allergies, or is on medication.
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Quick Amazon Picks: Best Dog Probiotics
| Product | Best For | Amazon Link |
|---|---|---|
| Zesty Paws Probiotic Bites | Daily digestive support | 👉 Check Price on Amazon |
| Nutramax Proviable-DC | Vet-recommended capsules | 👉 Check Price on Amazon |
| PetHonesty Probiotics | Digestive enzymes + probiotics | 👉 Check Price on Amazon |
| Zesty Paws Probiotic Soft Chews | Gut & immune health | 👉 Check Price on Amazon |
| Vet’s Best Probiotic Chews | Appetite & GI balance | 👉 Check Price on Amazon |
| PetLab Co. Probiotics | Yeast & allergy support | 👉 Check Price on Amazon |
| Pet Naturals Daily Probiotic | Best budget option | 👉 Check Price on Amazon |
| Zesty Paws Vet Strength Bites | Advanced gut support | 👉 Check Price on Amazon |
| Caninedophilus Probiotics | EFSA-approved strain | 👉 Check Price on Amazon |
| RX Buddy Biotics | Probiotic + prebiotic blend | 👉 Check Price on Amazon |
1. Zesty Paws Probiotic Bites for Dogs
These soft chews combine six probiotic strains, including the clinically studied DE111®, to support gut flora and digestion. Enhanced with pumpkin and papaya, they also aid in bowel movement and immune support.
Rating: 4.5/5 (4,800 reviews)
Price: $19.47Amazon Link: Zesty Paws Probiotic Bites for Dogs
2. Nutramax Proviable-DC Digestive Health Supplement
A capsule-based supplement featuring seven probiotic strains and prebiotics, designed to restore intestinal balance and support the immune system. Ideal for dogs experiencing digestive disturbances.
Rating: 4.6/5 (14,568 reviews)
Price: $17.15Amazon Link: Nutramax Proviable-DC Digestive Health Supplement
3. PetHonesty Probiotics for Dogs
These all-natural chews contain 6 billion CFUs per serving, combining pumpkin, probiotics, and digestive enzymes to alleviate diarrhea, constipation, and allergies. They also bolster immunity and overall health.
Price: $59.99Amazon Link: PetHonesty Probiotics for Dogs
4. Zesty Paws Probiotic Soft Chews
Formulated with six probiotic strains, including DE111®, these chews support gut function and maintain proper gut flora. The addition of pumpkin and papaya aids digestion and immune support.
Price: $61.77Amazon Link: Zesty Paws Probiotic Soft Chews
5. Vet’s Best Probiotic Soft Chews
Each chew delivers 1.5 billion CFUs from six strains of beneficial bacteria. Designed to maintain gastrointestinal balance, they support a healthy appetite and proper digestion.
Price: $33.00Amazon Link: Vet’s Best Probiotic Soft Chews
6. PetLab Co. Probiotics for Dogs
These daily chews support yeast production, seasonal allergies, intermittent itchiness, and digestive health. Suitable for small to medium-sized dogs.
Rating: 3.7/5 (259 reviews)
Price: $35.95Amazon Link: PetLab Co. Probiotics for Dogs
7. Pet Naturals Daily Probiotic for Dogs
A budget-friendly option, these chews support gut flora, immune health, and alleviate issues like diarrhea and itching. Suitable for daily use.
Rating: 4.6/5 (1,500 reviews)
Price: $9.99Amazon Link: Pet Naturals Daily Probiotic for Dogs
8. Zesty Paws Vet Strength Pre, Post & Probiotic Bites
Veterinarian-formulated, these chews feature VitaFiber™, LBiome™, Gingever™, and DE111® to provide supreme gut and immune support.
Price: $49.97Amazon Link: Zesty Paws Vet Strength Pre, Post & Probiotic Bites
9. CANINEDOPHILUS – Probiotics For Dogs
This product offers the only European Food and Safety Agency (EFSA) approved probiotic strain for dogs, ensuring efficacy and safety. Ideal for maintaining a healthy gut environment.
Price: $38.99Amazon Link: CANINEDOPHILUS – Probiotics For Dogs
10. Biomedic Labs RX Buddy Biotics Probiotic + Prebiotic
Combining 5 billion CFUs of probiotics with prebiotics, this supplement supports gut flora health, digestive and immune health, and provides relief from diarrhea and bowel issues.
Price: $38.25Amazon Link: Biomedic Labs RX Buddy Biotics Probiotic + Prebiotic
